35例胸膜间皮瘤临床分析

Clinical analysis of 35 cases of malignant pleural mesothelioma

目的探讨胸膜恶性间皮瘤的临床特点与治疗经验。方法回顾性分析中国医科大学附属第一医院1998年6月~2015年10月收治的35例胸膜恶性间皮瘤患者的临床资料。结果全部35例患者中,15例术前曾存在不同程度的误诊,误诊率为42.8%,1年生存率为60%,3年生存率为5.7%。大多数患者在术后3个月~1年复发,1年复发率为71.4%。结论胸膜恶性间皮瘤发病率低、恶性程度高、预后差,应根据患者疾病分期、病理分型、心肺功能等因素综合考虑,制订个体化治疗策略。

Objective To explore the clinical characteristics and treatment experience of malignant pleural mesothelioma. Methods The data of 35 cases of MPM were analyzed retrospectively in the First Hospital of China Medical University from June 1998 to October 2015. Results In all the patients, 15 cases was misdiagnosised, and the misdianosis rate was 42.8%. The 1-year-survival rate was 60% and the 3-year-survival rate was 5.7%. Most of the patients was recurrence during 3 months to 1 year after surgery, and the 1-year-recurrence rate was 71.4%. Conclusion MPM has low incidence, high grade malignance and bad prognosis. It should work out individualized treatment strategies considering the staging of disease, pathological type and cardiopulmonary function of each patient.