莫西沙星与左氧氟沙星治疗下呼吸道感染的疗效比较

Comparison of the Curative Effects of Moxifloxacin and Levofloxacin in the Treatment of Lower Respiratory Tract Infection

目的比较莫西沙星与左氧氟沙星治疗下呼吸道感染的临床效果。方法选取94例下呼吸道感染患者,随机分为对照组(47例)与观察组(47例),分别采取左氧氟沙星和莫西沙星治疗。统计两组患者喘息、发热、咳嗽等症状消失时间及住院天数,观察治疗效果。结果对照组与观察组治疗总有效率分别为91.5%和95.7%,比较无统计学意义(P>0.05)。较对照组,观察组喘息消失时间、发热消失时间、咳嗽消失时间及住院天数[(3.6±1.8)、(4.2±1.6)、(2.6±2.2)、(7.5±1.8)]d明显更优(P<0.05)。结论莫西沙星与左氧氟沙星治疗下呼吸道感染疗效相当,莫西沙星在迅速改善临床症状、促进患者康复方面更具优势。

Objective To compare the clinical effects of moxifloxacin and levofloxacin in the treatment of lower respiratory tract infection. Methods 94 patients with lower respiratory tract infection were randomly divided into the control group ( 47 cases ) and the observation group ( 47 cases ) and were treated with levofloxacin and moxifloxacin, respectively. The time of wheezing, fever, cough and other symptoms disappearing and the length of hospital stays in the two groups were statistically analyzed. The treatment effects were observed. Results The total effective rates of the observation group and the control group were 91. 5% and 95. 7%, respectively and the difference was not statistically significant ( P>0. 05). Compared with the control group, the time of wheezing, fever and cough disappearing and length of hospital stays in the observation group [ ( 3. 6 ± 1. 8 ) , ( 4. 2 ± 1. 6 ) , ( 2. 6 ± 2. 2 ) , ( 7. 5 ± 1. 8 ) ] d were significantly better ( P <0. 05 ) . Conclusion The curative effects of moxifloxacin and levofloxacin in the treatment of lower respiratory tract infection are similar. Moxifloxacin has more&nbsp;advantages in rapid improvement of clinical symptoms and promoting the rehabilitation of patients.