精神分裂症患者源记忆监控能力研究

Study on Source Memory Monitoring Ability of Patients with Schizophrenia

目的:探讨精神分裂症患者的源记忆监控能力,并研究患者源记忆监控能力和精神症状的相关性。方法:采用外部源记忆监控范式对47例处于疾病稳定期的精神分裂症患者和49名正常人的源记忆监控能力进行测试。使用阳性和阴性症状量表(PANSS)评估患者临床症状。结果:患者组项目记忆和源记忆正确率均显著低于对照组。患者组总体源记忆监控准确性和旧词源记忆监控准确性均显著低于对照组。相关分析显示,总体源记忆监控准确性和旧词源记忆监控准确性均与PANSS总分及阳性症状分呈显著负相关。结论:精神分裂症患者源记忆监控能力受损,源记忆监控能力与PANSS总分和阳性症状分呈负相关。

Objective： To explore the source memory monitoring ability of patients with schizophrenia, and the correla-tion between source memory monitoring ability and mental symptoms of patients. Methods： The source memory monitoringability of 47 patients with schizophrenia who were in stable stage and 49 healthy control subjects were tested by the externalsource memory monitoring task. The clinical symptoms of schizophrenic were assessed by the positive and negative symp-tom scale（PANSS）. Results： The correct rates of item memory and source memory of the patients were significantly lowerthan that of the control group. The accuracies of total source memory monitoring and old word source memory monitoring ofthe patients group were lower than those in the control group. The accuracies of total source memory monitoring and oldword source memory monitoring were negatively correlated with the total score of PANSS and positive symptom score. Conclusion： The source memory monitoring ability of patients with schizophrenia was impaired, and the source memory moni-toring ability was negatively correlated with both the total score of PANSS and positive symptom score.