糖尿病视网膜病变与凋亡相关因子的研究进展

Research progress of diabetic retinopathy and apoptosis- relating genes

细胞凋亡是一个复杂的多基因调控过程,其参与了糖尿病视网膜病变(diabetic retinopathy,DR)的发病机制,B细胞淋巴瘤/白血病2(B-cell leukemia/lymphoma-2,Bcl-2)、Fas等都是重要的凋亡调节基因。本文就DR与凋亡的关系及其某些相关基因的表达予以综述。

Researches have shown that cell apoptosis participates pathogenesis of diabetic retinopathy,which is a process of polygenes regulation. The B- cell leukemia / lymphoma- 2（ Bcl- 2） family and Fas are all important genes that can regulate apoptosis. This article reviews the relation between diabetic retinopathy and apoptosis as well as expression of some related genes.