潺槁木姜子地上部位化学成分

Chemical constituents from the aerial parts of Litsea glutinosa( Lour. ) C. B. Rob.

目的对樟科木姜子属植物潺槁木姜子[Litsea glutinosa(Lour.)C.B.Rob.]地上部位的化学成分进行研究。方法采用硅胶柱色谱、Sephadex LH-20凝胶柱色谱、高效液相色谱等技术对潺槁木姜子的化学成分进行分离,并采用核磁共振波谱等技术确证化合物的结构。结果从潺槁木姜子95%乙醇提取物乙酸乙酯部分获得5个化合物,并鉴定为pubinernoid A(I)、吐叶醇(II)、滨藜叶分药花苷(III)、1,2-dihydro-6,8-dimethoxy-7-1-(3,5-dimethoxy-4-hydroxyphenyl)-N1,N2-bis-[2-(4-hydroxyphenyl)ethyl]-2,3-naphthalene dicarboxamide(IV)和胡萝卜苷(V)。结论化合物I^IV为首次从潺槁木姜子中分离得到,并且化合物I^III为首次从木姜子属植物中分离得到。

Objective To study the chemical constituents from the aerial parts of Litsea glutinosa（ Lour.） C. B. Rob.Methods The obtained compounds were isolated by different chromatographic methods,including silica gel,Sephadex LH-20 and high performance liquid chromatography,and then their structures were elucidated on the basis of spectroscopic analyses,particularly the nuclear magnetic resonance spectroscopy. Results Five compounds were isolated from the Et OAc partition of the 95% Et OH extract of the aerial parts of Litsea glutinosa,and their structures were identified as pubinernoid A（ Ⅰ）,vomifoliol（Ⅱ）,atroside（ Ⅲ）,1,2-dihydro-6,8-dimethoxy-7-1-（ 3,5-dimethoxy-4-hydroxyphenyl）- N^1,N^2-bis-[2-（ 4-hydroxyphenyl） ethyl]-2,3-naphthalene dicarboxamide（ Ⅳ）, and daucosterol（ Ⅴ）.Conclusion Compounds I-Ⅳ are isolated from Litsea glutinosa for the first time,and compounds Ⅰ-Ⅲ are obtained from the genus of Litsea for the first time.