新生儿低血糖脑损伤临床特征15例分析

Clinical Characteristics Analysis of 15 Cases With Neonatal Hypoglycemic Brain Injure

目的总结和分析新生儿低血糖脑损伤的临床特征,探讨其危险因素。方法选择我院2013年1月~2015年12月收治的15例新生儿低血糖脑损伤患儿为观察组,选择同期我院收治的低血糖不伴脑损伤新生儿20例为对照组。回顾性分析两组患儿的临床资料。结果观察组和对照组患儿在胎龄、妊娠期糖尿病、低血糖持续时间、血糖水平、新生儿惊厥发生率及首次喂养时间等方面差异有统计学意义（P〈0.05）。结论新生儿低血糖性脑损伤可无临床症状或症状不典型,应重视早期监测和预防,尽量早期干预低血糖,减少脑细胞损害。

Objective To summarize and analyze the clinical characteristicsof neonatal hypoglycemic brain injury, and to explore its risk factors.Methods 15 cases of children with neonatal hypoglycemic brain injury in our hospital from January 2013 to December 2015 were chosen as the observation group, 20 cases at the same period were chosen as the control group. The clinical data of two groups were retrospectively analyzed.Results The difference of gestational age, gestational diabetes, the duration of hypoglycemia, blood glucose, neonatal seizures and the first feeding time between two groups was statistically significant（P0.05）. Conclusion It may be no clinical signs or the symptoms are not typical of neonatal hypoglycemic brain injure, which should be early detected and prevented,early intervened low blood sugar, to reduce brain damage.