瑞舒伐他汀对原发性高血压患者颈动脉粥样硬化影响及临床疗效观察

Observation of Clinical Effect and the Impact of Rosuvastatin on Carotid Atheroma in Patients With Primary Hypertension

目的探讨瑞舒伐他汀治疗原发性高血压患者颈动脉粥样硬化的效果。方法将90例原发性高血压颈动脉粥样硬化患者分为两组,对照组实行常规治疗,观察组在对照组的基础上实行瑞舒伐他汀治疗,比较两组的临床疗效。结果对照组的治疗总有效率(77.78%)低于观察组(93.33%),差异有统计学意义(t=8.654,P<0.05)。观察组治疗有效率,血脂水平等指标均优于对照组,差异有统计学意义(P<0.05)。结论瑞舒伐他汀能够显著改善颈动脉内膜中膜厚度。

Objective To observe the effect of rosuvastatin on carotid atherosclerosis with primary hypertension. Methods 90 cases of patients with primary hypertension were divided into two groups, control group was used about routine treatment, observation group was treated with rosuvastatin, to compare the treatment effect about two groups. Results The total rate of the treatment efficiency in the control group（77.78%） was lower than that in the observation group（93.33%）, the difference was statistically significant（t=8.654, P〈0.05）. The efficiency and blood lipid level of observation group were better than the control group（P〈0.05）. Conclusion Rosuvastatin can significantly improve the carotid artery intima media thickness.