从HR、PO_2、RVEDD、PAP、BNP对比分析尿激酶和瑞替普酶对急性肺栓塞的影响

Contrastive Analysis the HR,PO_2,RVEDD,PAP,BNP of Acute Pulmonary Embolism by Urokinase and Reteplase

目的探究从HR、PO_2、RVEDD、PAP、BNP对比分析尿激酶和瑞替普酶对急性肺栓塞的影响。方法将因急性肺栓塞入院接受溶栓治疗的患者46例随机分为两组,各23例,对照组给予尿激酶溶栓,观察组给予瑞替普酶溶栓治疗,24 h后观察临床各指标的变化。结果治疗后,两组患者HR、BNP、PAP、PO_2及VEDD均优于治疗前差异显著(P<0.05);观察组治疗后的RVEDD及BNP明显低于对照组,PO_2高于对照组,差异具有统计学意义(P<0.05);两组治疗后的心率、PAP比较,差异不明显(P>0.05)。结论采用瑞替普酶溶栓较尿激酶更能改善PE患者的RVEDD、BNP以及PO_2的指标,改善生存质量。

Objective Contrastive Analysis the HR,PO2,RVEDD,PAP,BNP of the acute pulmonary embolism by urokinase and reteplase.Methods The acute pulmonary embolism in hospitalized patients receiving thrombolytic therapy,46 patients were randomly divided into two groups,each of 23 patients in the control group given thrombolytic observation group was given the observation group,the clinical changes observed after each index 24 hours.Results After the treatment of 2 groups of patients with HR,BNP,PAP,PO2 and LVEDd was were better than before treatment significantly（P〈0.05）,observation of the treatment group after rvedd and BNP was lower than that of the control group,PO_2 was significantly higher than that of the control group,showed significant difference（P〈0.05）,after treatment in the two groups of heart rate,PAP difference inconspicuously（P〈0.05）.Conclusion Using reteplase thrombolytic therapy with urokinase can improve patients with PE rvedd,BNP and PO_2 index and improve the quality of life.