摘要
目的探讨奥氮平片治疗精神分裂症的疗效。方法研究组使用奥氮平片进行治疗,剂量以6 mg/d开始,后期增加剂量,最高用药剂量不超过35 mg/d。对照组使用氟哌丁苯进行治疗,药物剂量由8 mg/d开始,后期需视情况增加剂量,高用药剂量不超过70 mg/d。实验疗程为11周。结果使用奥氮平片治疗11周后,研究组有效率为84.9%,PANSS总分减分率为44.6%;采用氟哌丁苯治疗的对照组有效率为64.7%,PANSS总分减分率为31.4%。结论奥氮平片治疗精神分裂症效果较好,安全性强。
Objective To investigate the effect of Olanzapine tablets in the treatment of schizophrenia.Methods Research group used Olanzapine tablets for treatment,and started with the 6 mg/d,later increased the highest dose which can＇t exceed 35 mg/d.The contrast group were treated with haloperidol,and drug dosage started by 8 mg/d,later the maximum shall not exceed 70 mg/d.The course of treatment was 11 weeks.Results The use of Olanzapine tablets after 11 weeks of treatment,showing efficiency was 84.9%,the reduction rate of PANSS total score was 44.6%,haloperido1 display efficiency was 64.7%,the reduction rate of PANSS total score was 31.4%.Conclusion Olanzapine tablets has a clinical effect in the treatment of schizophrenia,and the safety is high.
出处
《中国继续医学教育》
2016年第10期149-150,共2页
China Continuing Medical Education
