老年髋部骨折患者死亡风险评价

Advancement of mortality prediction of aged hip fracture patients

随着老龄化社会的来临,老年髋部骨折发病人数激增,已成为一种具有巨大社会负担和经济负担的高危害性疾病。有学者认为将该类患者进行准确、有效的死亡风险程度分级,有利于对不同患者实施针对性的个体化治疗,从而间接改善患者预后。近年来有研究报道了多种与近远期死亡率密切相关的危险因素,包括人口学特征、基础病、临床干预措施、骨折后并发症等,并且在此基础上提出了多种特异性及非特异性骨折后死亡风险预测模型,对患病人群死亡风险的定量评估进行了初步探索,具有较大的临床参考价值。本文对近年来老年髋部骨折患者死亡风险评价方面的最新研究进展进行综述,以期为临床实践提供参考。

With the aging of the population, the incidence of geriatric hip fracturesincreases rapidly. And geriatric hip fracture has already become a potentially dangerous disease withheavy health and economic burden. Some researchers proposed that individualized treatment mightindirectly improve prognosis of this disease by accurate and effective risk classification. Recently, manyresearches explored the risk factors of short-term and long-term mortality in this population, includingdemographic features, pre-comorbidity, clinical intervention and post-fracture complications. In addition,several specific and non-specific multiple prediction models have also been proposed to achieve bettermortality prediction. These previous work gave a preliminary exploration for quantitative assessmentof mortality after hip fracture and obtained great clinical significance. In this paper, we hope to gives abrief review of the advancement in evaluating and predicting mortality in geriatric hip fracture patients andprovide a reference for clinical practice.