26例三脑室脑膜瘤的临床特点及诊治

Clinical features, diagnosis and treatment of third ventricle meningioma: An analysis of 26 cases

目的总结三脑室脑膜瘤的临床特点及诊治经验。方法回顾性分析首都医科大学附属北京天坛医院2000年2月-2015年6月26例三脑室脑膜瘤患者的临床资料,结合文献复习总结其诊断、治疗及预后。结果肿瘤位于三脑室前部9例、后部17例,全切除22例、次全切除4例,病理证实为脑膜瘤。出院时恢复正常14例,好转12例。随访时间1~15年,除1例死亡外,其余基本恢复正常。结论三脑室脑膜瘤少见,应当依据脑膜瘤在三脑室的前后位置选择手术入路,本组手术入路多为Poppen入路及纵裂-胼胝体-穹窿间入路。

Objective To review the experiences in diagnosis and treatment of third ventricle meningioma. Methods Clinical data about 26 patients with third ventricle meningioma in department of neurosurgery, Tiantan Hospital, Capital University of Medical University were analyzed retrospectively from February 2000 to June 2015, the clinical characteristics, the experience of diagnosis and treatment, and the prognosis were summarized, as well as its relevant literatures were reviewed. Results Nine meningiomas in the anterior third ventricle and 17 meningiomas in the posterior third ventricle were found. Gross total resection of the tumor was achieved in 22 patients, and subtotal resection was achieved in 4 patients, and the pathology diagnosis of this tumor was confirmed to be meningioma. Fourteen patients were healed and 12 patients’ condition were improved when discharged from hospital. All patients were healed except one patient died through a follow up of 1-15 years. Conclusion Meningioma of the third ventricle is a rare disease, a proper approach should be chosen according to the location of the meningioma. Poppen approach and the interhemispheric transcallosal interfornicial approach are common used in the operations of our study.