聚N-异丙基丙烯酰胺/海藻酸钠-核/壳结构微凝胶的制备与性能研究

Synthesis and characterization of PNIPAM/SA core-shell microgels

选用Ca2+交联的海藻酸钠(SA)为壳,以N,N-亚甲基双丙烯酰胺(BIS)交联合成的聚N-异丙基丙烯酰胺(PNIPAM)微凝胶为核,采用预凝胶法合成PNIPAM/SA-核/壳结构微凝胶。结果表明:当表面活性剂(SDS)用量为1%(摩尔百分数,下同),交联剂用量为2.5%时,得到稳定粒径大小的PNIPAM微凝胶。在PNIPAM/SA-核/壳结构微凝胶的合成过程中,不同的核/壳用量也影响最终的粒径大小。研究发现,当PNIPAM用量为20mL,SA用量为0.1g时,可以得到较小粒径的核/壳结构微凝胶。微凝胶的性质通过激光粒度分析仪(DLS)和透射电子显微镜(TEM)进行表征。

Core-shell microgels consisting of Poly（N-isopropylacrylamide）（PNIPAM）nanoparticles with N,N′-methylenebisacrylamide crosslinker as the core and Ca2＋cross-linked alginate as the shell was successfully synthesized by a pregel method.The results suggested that when the surface-activator at 1% mol and the crosslinker content at 2.5% mol,the microgels with stable size were obtained.For the synthesis of PNIPAM/SA nanoparticles,the different core-shell dosage also affected the final particle size.We found that the minimum particle size could be obtained when the dosage of PNIPAM was 20 mL and the consumption of SA was 0.1g.The characterization of microgels was studied by dynamic light scattering（DLS）and transmission electron microscopy（TEM）,respectively.