沈阳地区健康人群不同年龄段血清总IgE含量参考值范围的研究

Reference ranges of total serum IgE in different ages of healthy people in Shenyang area

目的：了解沈阳地区健康人群不同年龄段血清总IgE含量的参考范围。方法：采用酶联免疫吸附法（ELISA）对沈阳地区1529例健康人血清总IgE水平进行检测。结果：〈1岁组、1~6岁组、7~12岁组、13~18岁组、19~44岁组、45~60岁组及〉60岁组血清总IgE含量分别为（14.1±8.6）k U/L、（32.8±20.0）k U/L、（33.8±19.4）k U/L、（46.7±33.2）k U/L、（31.4±26.7）k U/L、（37.1±28.4）k U/L及（37.9±32.8）k U/L。结论：沈阳地区健康人群不同年龄段总IgE含量水平存在差异,总IgE水平在婴幼儿年龄段较低,到成年达到最高值,随后至中老年又呈下降趋势。该文初步建立了沈阳地区不同年龄段健康人血清总IgE值的参考区间,为该地区的过敏性疾病的诊治提供参考。

Objective： To establish the reference ranges of total IgE in different ages of healthy people in Shenyang area. Methods： The total serum IgE levels were measured with ELISA in 1529 healthy people in different ages. Results： The total IgE levels in 7 age groups（〈l year old, 1-6 years old, 7-12 years old, 13-18 years old, 19-44 years old, 45-60 years old, and 〉60 years old） were （14.1±8.6）kU/L, （32.8±20.0）kU/L, （33.8±19.4）kU/L, （46.7±33.2）kU/L, （31.4±26.7）kU/L, （37.1±28.4） kU/L and （37.9±32.8） kU/L, respectively. Conclusions： Total IgE serum levels vary significantly with ages in heahhy people. The total IgE levels are lower in the infants and peak at adulthood, followed by a gradual decline as aging. The ref- erence ranges of total serum IgE are established for healthy people in Shenyang region, providing a reference for the diagno- sis and treatment of allergic disease in certain regions.