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狼疮抗凝物实验室规范化检测进展 被引量：8

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摘要 狼疮抗凝物(lupus anticoagulants,LAC)是一类针对带负电荷磷脂或磷脂与蛋白质复合物的自身抗体,其持续阳性预示动静脉血栓以及习惯性流产等不良事件的发生,此外可作为抗凝治疗效果的监测指标。但由于分析前、分析中诸多因素(如样本的准备、筛查试验的检测试剂和方法选择)影响检测结果的准确性和重复性,其临床应用效果不太理想。本文依据国际血栓与止血学会(ISTH)、英国血液学标准委员会(BCSH)以及临床实验室标准化协会(CLSI)等相关指南及文献,对LAC实验室检测相关问题作一综述。
作者 谢波 徐升强 崔天盆
机构地区 武汉市第一医院检验科
出处 《临床检验杂志》 CAS CSCD 2016年第2期144-146,共3页 Chinese Journal of Clinical Laboratory Science
关键词 狼疮抗凝物 影响因素 规范化
分类号 R446 [医药卫生—诊断学]
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参考文献25

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二级参考文献21

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共引文献17

同被引文献44

引证文献8

二级引证文献10

临床检验杂志
2016年 第2期

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