腕表式动态血氧仪对阻塞性睡眠呼吸暂停低通气综合征筛查价值的研究

Evaluation of CMS50F as a screening test for patients with obstructive sleep apnea hypopnea syndrome

目的探讨腕表式动态血氧仪(CMS50F)用于阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者筛查的临床价值。方法 64例研究对象同时进行多导睡眠图(PSG)、微动敏感床垫式睡眠监测系统(MSMSMS)和CMS50F监测,分别以PSG和MSMSMS监测的呼吸暂停低通气指数(AHI)为诊断OSAHS的标准,评估CMS50F监测睡眠的可靠性。结果正常及轻、中度患者监测的CMS50F-氧减饱和度指数(ODI3)与PSG-AHI差异无统计学意义,重度患者CMS50F-ODI3小于PSG-AHI(P<0.05)。但CMS50F-ODI3与PSG-AHI呈正相关(r=0.855,P<0.05)。以PSG-AHI≥5次/h为阳性阈值,CMS50F检测的敏感度为94.5%,特异度为88.9%。正常及轻、中度患者监测的CMS50F-ODI3与MSMSMS-AHI差异无统计学意义,重度患者CMS50F-ODI3小于MSMSMS-AHI(P<0.05),但两者密切相关(r=0.867,P<0.05)。以MSMSMS-AHI≥5次/h为阳性阈值,CMS50F检测的敏感度为94.5%,特异度为88.9%。结论腕表式动态血氧仪CMS50F可作为一种可靠的筛查OSAHS的便携式工具。

Objective To evaluate the diagnostic accuracy of CMS50 F for screening in patients with obstructive sleepapnea-hypopnea syndrome（OSAHS）. Methods Sixty-four volunteers with suspected OSAHS underwent simultaneous noc-turnal polysomnography（PSG）, micromovement sensitive mattress sleep monitoring system（MSMSMS）and CMS50 F. The ap-nea-hypopnea index（AHI） detected by PSG and MSMSMS was used as the diagnostic standard for OSAHS. The reliability ofCMS50 F for monitoring sleep was assessed. Results There was no statistic difference in CMS50F-ODI3 and PSG-AHI be-tween normal, mild and moderate OSAHS groups（P 0.05）. The CMS50F-ODI3 was smaller than the PSG-AHI in severeOSAHS patients（P 0.05）. There was a positive correlation between CMS50F-ODI3 and PSG-AHI（r=0.855, P 0.05）.PSG-AHI≥5 events per hour was used as the threshold value to diagnose OSAHS, the sensitivity and specificity of CMS50 Fwere 94.5% and 88.9%. There were no significant differences in CMS50F- ODI3 and MSMSMS-AHI between normal, mildand moderate OSAHS patients（P 0.05）. The value of CMS50F-ODI3 was smaller than MSMSMS-AHI in severe OSAHSpatients（P 0.05）. There was also a significant correlation between CMS50F- ODI3 and MSMSMS- AHI（r=0.867,P 0.05）. MSMSMS-AHI≥5 events per hour was used as the threshold value to diagnose OSAHS, the sensitivity and specificityof CMS50 F were 94.5% and 88.9%. Conclusion CMS50 F can be used as a portable and reliable device for screening of pa-tients suspected OSAHS.