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IVF-ET中非整倍体胚胎代谢的生物学标志物研究进展 被引量：1

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摘要 自从1978年首例试管婴儿诞生,IVF-ET（in vitro fertilization-embryo transplant,IVF-ET）已成为治疗不孕症最重要的方法之一。国内外接受IVF治疗的夫妇数快速增加,一方面,尽管IVF结局得到巨大的改善,但它们的有效性,以正常活婴出生率计算大约30%。
作者 贾婵维 王树玉
机构地区 首都医科大学附属北京妇产医院生殖中心
出处 《中国优生与遗传杂志》 2016年第4期3-4,共2页 Chinese Journal of Birth Health & Heredity
基金 北京市教育委员会科技计划面上项目(KM2014002 5024)
关键词 非整倍体 IVF-ET 生物学标志物 fertilization embryo 胚胎植入 TRANSPLANT 生物学指标 脂质运载蛋白 卵裂球
分类号 R714.8 [医药卫生—妇产科学]
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参考文献15

  • 1贾婵维,兰永连,司艳梅,马延敏,梁毓,王威,余兰,李颖,王树玉.胎儿染色体异常相关因素分析[J].中华医学遗传学杂志,2013,30(5):635-637. 被引量：26
  • 2Ramos L, et al. Does the S phase have an impact on the accuracy of comparative genomic hybridization profiles in single fibroblasts and human blastomeres?[J].Fertil Steril, 2014, 101,488-495.
  • 3Fragouli E, Alfarawati S, Spath K, et al. Morphological and cytogenetic assessment of cleavage and blastocyst stage embryos[J]. Mol Hum Reprod, 2014, 20 ( 2 ) : 117-26.
  • 4Mertzanidou A, Spits C, Nguyen HT, et al. Evolution of aneuploidy up to Day 4 of human preimplantation development[J].Hum Reprod, 2013, 28:1716-1724.
  • 5Fragouli E, Wells D. Aneuploidy in the human blastocyst[J]. Cytogenet Genome Res, 2011,133 : 149-159.
  • 6Alfarawati S, Fragouli E, Coils P, et al. The relationship between blastocyst morphology, chromosomal abnormality, and embryo gender[J].Fertil Steril, 2011,95 ( 2 ) :520-4.
  • 7Hardarson T, Hanson C, Lundin K, et al. Pre-implantation genetic screening in women of advanced maternal age caused a decrease in clinical pregnancy rate :a randomized controlled trial[J].Hum Reprod, 2008,23:2806-12.
  • 8Sebastiaan Mastenbroek, Sjoerd Repping. Preimplantation genetic screening :back to the future[J].Human Reproduction, 2014, 29 (9): 1846- 1850.
  • 9David K Gardner, Petra L Wale. Analysis of metabolism to select viable human embryos for transfer[J].Fertility and Sterility, 2013, 99 (4) :1062-1072.
  • 10Katz-Jaffe MG, McReynolds S. Embryology in the era of proteomics[J].Fertil Steril, 2013,99 (4) :1073-7.

二级参考文献16

  • 1郭小宝,阮永铭,李文典,崔娓.9号染色体臂间倒位的遗传效应分析[J].中华医学遗传学杂志,2006,23(3):365-365. 被引量：38
  • 2Bower C,Rudy E,Callaghan A,et al. Age at diagnosis of birthdefects. Birth Defects Res A Clin Mol Teratol, 2010, 88: 251-255.
  • 3Bombard AT,Powers JF,Carter S, et al. Procedure-related fetallosses in transplacental versus nontransplcental geneticamniocentesis. Am J Obstet Gynaecol, 1995,172:868-872.
  • 4Van Opstal D,van den Berg C,Galjaard RJ, et al. Follow upinvestigation in uncultured amnicotic fluid cells after uncertaincytogenetic results. Prenat Diagn, 2001,21 :75-80.
  • 5Schrock E,du Manior S,Veldman T,et al. Multicolor spectralkaryotyping of human chromosome. Science,1996,273: 494-497.
  • 6American College of Obstetricians and Gynecologists. ACOGPractice Bulletin No. 88, Invasive prenatal testing foraneuploidy. Obstet Gynecol, 2007,110: 1459-1467,.
  • 7Merkatzz IR,Nitowsky HM, Macri JN, et al. An associationbetween low maternal serum a~fetoprotein and fetal chromosomalabnormalities. Am J Obstet Gynecol, 1984,148 : 886-894.
  • 8Sailer DN Jr,Canick JA. Current methods of prenatal screeningfor Down Syndrome and other fetal abnormalities. Clin ObstetGynecol, 2008, 51 : 24-36.
  • 9Ehrich M,Deciu C,Zwiefelhofer T,et al Noninvasive detectionof fetal trisomy 21 by sequencing of DNA in maternal blood: astudy in a clinical setting. Am J Obstetr Gynecol, 2011,204:205. el-11.
  • 10Chen EZ,Chiu RW, Sun H, et al. Noninvasive prenataldiagnosis of fetal trisomy 18 and trisomy 13 by maternal plasmaDNA sequencing. PLoS One, 2011,6 : e21791.

共引文献25

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中国优生与遗传杂志
2016年 第4期

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