摘要
目的:了解笔者所在医院儿科以消化道症状就诊儿童幽门螺杆菌(H.pylori)的感染状况及分布特征。方法:采用13C-尿素呼气试验(13C-UBT)对笔者所在医院儿科门诊2013年6月-2014年6月收治的以消化道症状就诊儿童H.pylori感染状态进行检测,采用调查表收集患儿家庭经济状况、卫生习惯、饮水情况、父母的健康情况等。分类变量的组间比较采用Pearson字2检验。结果:422例受检儿童中H.pylori感染阳性者115例,感染阳性率为27.25%。197例男童中,感染阳性者59例,阳性率为29.94%;225例女童中,感染阳性者56例,阳性率为24.89%。不同年龄段及性别的感染阳性率比较差异均无统计学意义(P>0.05)。115例感染阳性者中有83例(72.17%)患儿的家庭成员曾患或现有消化道炎症或溃疡,而307例感染阴性者中仅有122例(39.74%)患儿的家庭成员患病,差异有统计学意义(P<0.001)。结论:笔者所在医院儿科就诊儿童H.pylori感染阳性率低于国内报道平均水,但仍高于发达国家平均水平,呈明显的家庭聚集性。
Objective：To investigate the H.pylori infection status and distribution characteristics of children with gastrointestinal symptoms treated in pediatric outpatient of our hospital.Method：^13C-UBT was used to evaluate the infection status of children treated in pediatric outpatient from June 2013 to June 2014,and questionnaire was used to collect data of family economic status,health habits,drinking status and health conditions of family members.Pearson x^2 test was used for comparison of categorical variables between groups.Result：A total of 422 children were tested,and 115 cases of them were infected with H.pylori,the positive rate of infection was 27.25%.Fifty-nine cases in 197 boys were positive,the positive rate was 29.94%,and 56 cases in 225 girls were positive,the positive rate was 24.89%.There were no statistically significant differences in the positive rate of infection between different age or gender groups（P〈0.05）.Among the 115 infected children,83 cases（72.17%） of them had family members suffered or with gastrointestinal ulceration or inflammation currently,while in 307 uninfected children,the proportion of family factor（122/307,39.74%） was significantly lower,the difference was statistically significant（P〈0.001）.Conclusion：The proportion of H.pylori infected children in pediatric outpatient is relatively lower than domestic average level but still higher than that of developed countries,and there is a significant familial aggregation.
出处
《中外医学研究》
2016年第12期12-14,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
