银杏叶注射液对甲状腺癌术后伴甲减患者血清β_2-MG、IL-6及甲状腺功能影响研究

Effect on Serum β_2-MG,IL-6 and Thyroid Function by Ginkgo Biloba Injection in Patients after Operation of Thyroid Cancer with Hypothyroidism

目的:探究银杏叶注射液对甲状腺癌术后伴甲减患者血清β2-MG、IL-6及甲状腺功能影响。方法:收集我院肿瘤科甲状腺癌患者76例,随机分为对照组和实验组。两组患者均进行甲状腺手术治疗,并于手术后实施葡萄糖注射液配合葡萄糖酸钙注射液,治疗组患者在此基础上注射银杏叶注射液。患者治疗前后血清β2-MG、IL-6及甲状腺功能进行对比分析。结果:治疗后两组β2-MG水平明显下降(P<0.05),IL-6水平下降(P<0.05),i PTH水平下降(P<0.05),TC、HDL-C以及LDL-C水平下降(P<0.05);与对照组相比,治疗组β2-MG水平较低(P<0.05),IL-6水平较低,PTH水平较高,TC、HDL-C以及LDL-C水平较低(P<0.05)。结论:银杏叶注射液可缓解甲状腺癌术后伴甲减症状,改善预后。

Objective：To investigate the effect on serum β2-MG,IL-6 and thyroid function by ginkgo biloba injection in patients after operation of thyroid cancer with hypothyroidism. Method：76 thyroid cancer patients from Oncology Department of our hospital were selected and randomly divided into the control group and the experiment group.Two groups were treated by glucose injection combined with calcium and glucose injection and the experiment group added ginkgo biloba injection.The serum β2-MG,IL-6 and thyroid function were compared before and after treatment. Result：Compared with before treatment,the β2-MG level were lower,（P〈0.05）,the IL-6 level were lower,（P〈0.05）,the i PTH level were lower,（P〈0.05）.Compared with the control group after treatment,the β2-MG level were lower,（P〈0.05）,the IL-6 level were lower,（P〈0.05）,the PTH level were higher,（P〈0.05）.Conclusion：Ginkgo biloba injection on symptoms of hypothyroidism with thyroid cancer postoperative relief of postoperative thyroid carcinoma,prognosis.