绝经后妇女膝关节骨性关节炎和骨质疏松症发生率关系

Relationship between knee osteoarthritis and osteoporosis in postmenopausal women

目的研究分析绝经后妇女骨质疏松症和膝关节骨性关节炎发生率关系。方法回顾性分析100例绝经后骨质疏松患者以及100例绝经后骨关节炎患者的基本资料,对患者的年龄、体重指数进行计算,做好骨密度的测定,对两组患者的骨质疏松以及骨关节炎等指标的变化进行比较。结果观察A组中的100例骨质疏松患者88例为II度以上的骨性关节炎。同时观察B组中的100例骨性关节炎患者中25例腰椎和髋部骨密度逐渐下降,其T值小于-2.5SD,确诊为骨质疏松症。随着年龄的增长,绝经后妇女骨质疏松和骨质增生伴发率逐渐增加,同时绝经后妇女的体重指数和骨密度以及骨关节炎有着正相关的关系,绝经后妇女骨质疏松体重指数较大的,并合并骨性关节炎患者的发生率逐渐增加,骨性关节炎患者体重指数较低,骨质疏松发生的可能性较大。结论绝经后妇女骨质疏松和骨性关节炎的发生,和年龄有密切的关联,同时骨性关节炎是骨质疏松症发生的一种重要影响因素。

Objective To study the relationship between osteoporosis and osteoarthritis of the knee joint in postmenopausal women. Methods The basic data of 100 cases of postmenopausal osteoporosis patients and 100 cases of postmenopausal patients with osteoarthritis were retrospectively analyzed. The age and weight index of the patients were calculated. Bone mineral density was determined. The changes in the index between the two groups were compared. Results In group A,osteoarthritis of II degree or above were observed in 88 cases of 100 cases of osteoporosis. At the same time,bone mineral density of the lumbar vertebrae and the hip decreased in 25 cases of 100 patients with osteoarthritis in group B,and their T values were less than- 2. 5 SD which was diagnosed as osteoporosis. With increase of age,the incidence of osteoporosis and hyperosteogeny in postmenopausal women increased gradually. Body mass index was positively correlated with bone mineral density（ BMD） and osteoarthritis in postmenopausal women. The incidence of osteoarthritis increased in postmenopausal women with osteoporosis and larger BMI. The occurrence of osteoporosis was more in patients with osteoarthritis and lower body mass index. Conclusion The occurrence of osteoporosis and osteoarthritis is closely related to age of postmenopausal women. Osteoarthritis is one of the most important factors of the occurrence of osteoporosis.