有氧运动与雷洛昔芬联合治疗对老年骨质疏松症的改善作用

The effect of aerobic exercise and raloxifene treatment on senile osteoporosis

目的对有氧运动与雷洛昔芬联合治疗老年骨质疏松症的效果进行分析,探讨有氧运动与雷洛昔芬联合治疗老年骨质疏松症比单纯采用有氧运动或者雷洛昔芬的有效性。方法选取2013年4月-2014年8月期间延安大学附属医院骨外科门诊收治的70例老年骨质疏松患者为研究对象,按照治疗方式不同分为:观察组35例,对照组35例。对照组为雷洛昔芬治疗组,观察组在对照组的基础上加有氧运动组。结果与对照组比较,观察组L2-L4的各项指标都显著优于对照组(P<0.01),有统计学意义。结论有氧运动联合雷洛昔芬治疗老年性骨质疏松症松比单独应用能获得更好的效果,并且更加安全易行,值得进一步研究并在临床推广。

Objective To analyze the effect of combination of aerobic exercise with raloxifene for the treatment of senile osteoporosis,and to explore the efficacy of combined treatment,aerobic exercise or raloxifene alone,on senile osteoporosis.Methods A total of 70 cases of senile osteoporosis in the outpatient of the Affiliated Hospital,Yanan University,were studied from April 2013 to August 2014. According to the different treatment,they were divided into observation group（ 35 cases） and control group（ 35 cases）. Patients in the control group received raloxifene treatment. Patients in the observation group received raloxifene and aerobic exercise. Results After the treatment,all the parameters in L2-L4 were better in the observation group than in the control group,with statistical significance（ P 〈0. 01）. Conclusion Aerobic exercise combined with raloxifene treatment has better effect on senile osteoporosis comparing with single treatment. It is safe and convenient in use and worth of further study and clinical application.