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SpitSpitz痣-例并相关文献复习

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摘要 患儿,女性,5岁8月,右侧面颊部5年前发现小米粒样褐色丘疹,始无疼痛、瘙痒,未行处理,近一年明显增大,无自觉症状,因影响外观并怀疑恶变,来我院就诊.专科检查:右侧面颊部约0.4cm×0.4cm隆起包块,红褐色,孤立存在,无毛发生长,无压痛,无破溃.临床处理:适当扩大切除病变组织.病理检查结果考虑为Spitz痣(上皮样细胞型),免疫组织化学示:melant(+),S-100(+),HMB-45局灶少数细胞(+),ki-67阳性率约为2%(图二).
出处 《中华临床医师杂志(电子版)》 CAS 2016年第7期17-18,共2页 Chinese Journal of Clinicians(Electronic Edition)
关键词 皮肤肿瘤 诊断
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参考文献10

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二级参考文献7

  • 1纪小龙,缪德标,李维华.无色素性恶性黑色素瘤的形态多样性[J].诊断病理学杂志,1995,2(4):201-202. 被引量:21
  • 2Krasovec M, Gianadda B, Hohl D. Giant recurrence of a multiple agminated Spitz nevus. J Am Acad Dermatol 1995;33(2Pt 2):386 - 388.
  • 3Ferrara G, Argenziano G, Soyer HP, et al. The spectrum of Spitz nevi: a chnicopathologic study of 83 cases. Arch Dermatol 2005; 141(11) :1381 - 1387.
  • 4朱学骏,孙建方.皮肤病理学与临床的联系.第3版.北京:北京大学医学出版社,2007.1268-1275.
  • 5Binder SW, Assonant C, Paule E, et al. The histology and differential diagnosis of spitz nevus. Semin Diagn Pathol 1993; 10:36 - 46.
  • 6Bergman R, Dromi R, Trau H, et al. The pattern of HMB-45 antibody staining in compound spitz nevi. Am J Dermatopathol 1995; 17:542 - 546.
  • 7Bergman R, Malkin L, Sabo E, et al. MIB- 1 monoclonal antibody to determine proliferative activity as an adjunct to the histopathologic differential diagnosis of spitz nevus. J Am Acad Dermatol 2001 ;44: 500 - 504.

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