曲安奈德与丝裂霉素在复发性翼状胬肉切除术后应用的效果观察

目的 探讨曲安奈德与丝裂霉素在复发性翼状胬肉切除术围手术期的应用效果.方法 回顾性分析35 例（42 只眼）复发性翼状胬肉,所有病例均先行显微镜下翼状胬肉切除联合自体角膜缘干细胞移植术.所有病例随机分为两组（观察组及对照组）.观察组 18 例（21 只眼）曲安奈德4mg 于术毕及术后1 月局部结膜下注射.对照组： 17 例 （21 只眼）,行术中丝裂霉素局部湿敷.结果 术后随访6 个月,观察组中1 例（4.8%）翼状胬肉复发.对照组4 例（19.0%）翼状胬肉复发（ P〈0. 05）,有显著差异,提示与丝裂霉素相比应用曲安奈德能降低翼状胬肉术后的复发率.结论 与丝裂霉素相比,曲安奈德结膜下注射可以作为复发性翼状胬肉切除术后减少其再次复发的常规应用.

Objective To investigate the triamcinolone acetonide and mitomycin in recurrent pterygium resection of application effect. Methodsa retrospective analysis of 35 cases （42 eyes） with recurrent pterygium, all cases were first microscope pterygium excision with autologous limbal stem celltransplantation. And then randomly divided into two groups （observation group and control group）. Observation group 18 cases （21 eyes） receivedsubconjunctival injection of 4mg triamcinolone at the end of surgey and postoperative 1 month.Control group： 17 cases （21 eyes）, intraoperativemitomycin local hydropathic compress. Results postoperative follow-up of 6 months, 1 case in the observation group （4.8%）, recurrence of pterygium.Control group in 4 cases （19.0%）, recurrent pterygium （P 〈 0. 05）, there are significant differences, prompt compared with mitomycin applicationtriamcinolone acetonide can reduce the postoperative recurrence rate of pterygium. Conclusion compared with mitomycin, triamcinolone acetonidesubconjunctival injection can be used routinely to reduce recurrent pterygium replace after the resection.