忍冬叶环烯醚萜苷类化学成分研究

Chemical constituent analysis of iridoid glycosides from leaves of Lonicera japonica Thunb.

利用硅胶、Sephadex LH-20以及制备液相色谱等方法进行分离纯化,从忍冬叶中分离得到3个环烯醚萜苷类化合物,以及β-谷甾醇和胡萝卜苷。通过理化性质、波谱数据分析,分别鉴定为裂环马钱素酸、demethylsecologanol、裂环马钱素、β-谷甾醇和胡萝卜苷,其中化合物demethylsecologanol为首次从该属植物中分离得到。

Three iridoid glycoside compounds were purified and isolated from leaves of Lonicera japonica Thunb. （L. japonica） with silica gel, sephadex LH-20 and preparative HPLC. Through analysis of spectrum data and physicochemica properties, we identified them as secoxyloganin, demethylsecologanol, secologanin, β-sitosterol and daucosterol. Compound demethylsecologanol is originally isolated from Lonicera.