盐酸氨溴索静脉用药协同雾化吸入治疗29例老年呼吸系统感染性疾病疗效观察

The effect of intravenous infusion of ambroxol hydrochloride collaborated with inhalation in the treatment of 29 cases of the elderly respiratory infectious disease

目的:观察盐酸氨溴索雾化吸入治疗老年呼吸系统感染性疾病的效果。方法:收集2014年7月-2015年6月年龄>80岁的老年呼吸系统感染性疾病患者58例,随机分为治疗组29例,静脉滴注盐酸氨溴索60 mg,每天1次,同时雾化吸入盐酸氨溴索15 mg,每天2次,每次15 min;对照组29例,静脉滴注盐酸氨溴索60 mg,每天1次。两组均给予常规抗生素和解痉平喘治疗,观察两组治疗效果。结果:治疗组总有效率为86.21%(25/29),显著高于对照组的75.86%(22/29,P<0.05)。临床体征咳嗽、咳痰好转或终止时间短于对照组,肺部啰音消失时间快于对照组,抗生素使用时间短于对照组。结论:盐酸氨溴索静脉用药协同雾化吸入治疗老年呼吸系统感染性疾病起效快,且安全,值得临床推广。

Objective：To observe the effect of inhalation of ambroxol atomization in the treatment of the elderly respiratory infectious disease.Methods：From July 2014 to June 2015,58 elderly cases of the respiratory infectious diseases were collected and randomly divided into a treatment group with 29 cases who were treated with ambroxol hydrochloride（intravenous infusion of 60 mg daily and inhalation of 15 mg twice a day with 15 min each）.The control group with 29 cases intravenously received 60 mg of ambroxol hydrochloride daily.The two groups were treated with the conventional antibiotics and antispasmodic asthma.Results：The total effective rate of the treatment group was 86.21%（25/29）,which was significantly higher than 75.86%（22/29） of the control group（P〈0.05）.The improvement or termination time of the clinical signs such as cough and expectoration were shorter in the treatment group than in the control group.The pulmonary rales disappeared faster in the treatment group than in the control one.The duration of antibiotics was shorter in the treatment group than in the control one.Conclusion：The effect of intravenous infusion of ambroxol hydrochloride collaborated with inhalation in the treatment of the elderly respiratory infectious disease is rapid and safe,which is worthy of clinical promotion.