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前列地尔注射液对老年患者冠脉介入治疗术后对比剂肾病的预防 被引量:18

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摘要 目的:探讨前列地尔对老年冠心病患者PCI术后对比剂肾病的预防作用。方法:选择我院心内科住院老年冠心病患者217例,按照入院顺序作为编号,依据随机数字表法随机分为常规组(107例,常规治疗)和前列地尔组(110例,前列地尔注射液+常规治疗)。观察2组患者PCI术前及术后72 h血肌酐、尿素氮、胱抑素C水平的变化,分析2组患者对比剂肾病发病情况。结果:前列地尔组PCI术后对比剂肾病发病率低于常规组(2.7%vs 9.3%),差异有统计学意义(P<0.05);PCI术后72 h前列地尔组血肌酐及胱抑素C水平低于常规组,差异有统计学意义(P<0.05)。结论:前列地尔注射液可能对老年冠心病患者PCI术后对比剂肾病有预防作用,但还需要更大样本的随机对照研究进一步证实。
出处 《实用医学杂志》 CAS 北大核心 2016年第7期1164-1166,共3页 The Journal of Practical Medicine
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参考文献16

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