妊娠后半期甲状腺功能异常孕妇287例妊娠结局临床分析

Clinical analysis of pregnancy outcome in 287 cases of abnormal thyroid function in the second half of pregnancy

目的分析妊娠后半期甲状腺功能异常孕妇的妊娠结局。方法选取2014年10月至2015年10月于我院待产的287例孕妇,根据孕妇甲状腺功能检测结果将其分为临床甲减组、亚临床的甲减组(简称亚甲减组)和对照组,对所有孕妇的妊娠结局进行观察和记录。结果临床甲减组孕妇发生贫血、胎盘早剥、妊高症和早产的风险明显高于对照组(P<0.05);亚甲减组孕妇发生胎盘早剥和妊高症的风险明显高于对照组(P<0.05)。结论妊娠合并甲减或亚临床甲减孕妇发生妊娠不良结局概率较高,因此有必要对待产孕妇进行甲功筛查,以便及时对甲减与亚临床甲减进行诊治。

Objective To analysis the relationship between the thyroid function and abnormal pregnancy outcome in second half of pregnancy. Methods Two hundred and eighty-seven cases of pregnant women in our hospital from October 2014 to October 2015 were divided into three groups： clinical hypothyroidism group, subclinical hypothyroidism group and nor-mal control group. The pregnancy outcomes were observed and recorded. Results Compared with the control group, the risk of anemia, placental abruption, preeclampsia and preterm delivery of pregnant women in hypothyroidism group are signifi-cantly higher（P〈0.05）; the risk of placental abruption and pregnancy induced hypertension in subclinical hypothyroidism group of pregnant women is significantly higher than that of the control group（P〈0.05）. Conclusion Pregnancy complicated with hypothyroidism or subclinical hypothyroidism in pregnant women has increased the probability of adverse outcomes in pregnancy. Screen for thyroid function in pregnant women is necessary for timely treatment.