摘要
瘙痒是特应性皮炎(AD)患者必备的临床表现,其特征表现为红斑伴随瘙痒、痒觉敏感、痒觉异常以及夜间瘙痒等。AD瘙痒发生与众多的炎症介质、炎性细胞、神经免疫相互作用以及皮肤屏障障碍等有关。理解AD瘙痒的病理生理,为临床开展治疗提供帮助。
Itch is an essential clinical feature of atopic dermatitis. There are several aspects defining itch in patients with AD. Besides itch associated with erythema,alloknesis,atmokensis and nocturnal itch are often observed. It is known that many inflammatory mediators,inflammatory cells,neuroimmunological interaction and disturbed skin barrier are involved in the itch of AD. Understanding of pathophysiology of itch are benificial to managements of itch in AD.
出处
《中国医学文摘（皮肤科学）》
2016年第2期144-147,90,共4页
China Medical Abstracts(Dermatology)
关键词
特应性皮炎
瘙痒
病理生理
Atopic dermatitis
Itch
Pathophysiology
