摘要
特应性皮炎(atopic dermatitis,AD)是一种慢性和复发性炎症性皮肤病,目前认为主要是皮肤屏障功能障碍、免疫应答异常和环境因素刺激共同作用的结果。AD的实验室检查包括过敏原检测、炎症指标和皮肤屏障功能的检查。由于AD涉及的免疫学机制是IgE介导和非IgE介导的混合性免疫学机制,故AD病人过敏原检测常用的方法是皮肤点刺试验、特应性斑贴试验、特异性Ig E检测,建议同时进行体内和体外过敏原检测,检测结果应结合病史和临床症状来分析。与特应性皮炎相关的微生物感染主要是金黄色葡萄球菌、马拉色菌、白念珠菌和单纯疱疹病毒感染。临床上也可作相关的病原学和炎症指标检查。
Atopic dermatitis（ AD） is a chronic and relapsing inflammatory skin disease. It is now thought that the skin barrier dysfunction and immunologic dysregulation and environmental factors result jointly in AD inflammation. Laboratory tests in AD have the examinations about allergen,inflammation markers and skin barrier function. The allergen detecting methods in AD patients are commonly skin prick test,atopic patch test and specific Ig E,because the immunological mechanisms of AD involved in IgE mediated and non IgE mediated mixed immunological mechanisms. It is suggested that patients with AD are gived the allergen tests in vivo and in vitro at the same time,thatthe analysis of test results should be combined to the history and clinical symptoms.The main microbial infection associated with atopic dermatitis is staphylococcus aureus,marla color bacteria,candida albicans and herpes simplex virus,relevant etiology and inflammation markers are gived to the patients in AD clinically.
出处
《中国医学文摘（皮肤科学）》
2016年第2期174-179,91,共6页
China Medical Abstracts(Dermatology)
