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足细胞裂孔隔膜相关蛋白分子研究进展 被引量:3

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摘要 肾小球滤过屏障可以阻止血浆蛋白进入尿液,由血管内皮细胞、肾小球基底膜和足细胞(足突)构成。而足细胞足突间的裂孔隔膜(slit diaphragm,SD)是构成肾小球滤过屏障结构及功能完整性的最重要组成部分,亦是限制蛋白滤过的关键部位。近年随着对肾小球滤过屏障机制的深入研究,已发现多种重要的足细胞相关蛋白。本文就足细胞具有代表性的几类相关蛋白结构特征、功能做一综述。
作者 王娜 魏日胞
出处 《中国中西医结合肾病杂志》 2016年第3期266-268,共3页 Chinese Journal of Integrated Traditional and Western Nephrology
基金 国家自然科学基金资助项目(No.81273968,81471027和81401160) 301百项优势项目(No.YS201408)
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