鼻腔冲洗治疗孕产妇变应性鼻炎的疗效观察

Clinica observationg of nasal irrigation in the the treatment of allergic rhinitis in pregnant women

目的鼻腔冲洗治疗变应性鼻炎的孕产妇疗效,探讨鼻腔冲洗在孕产妇变应性鼻炎(AR)治疗中的作用。方法将35例孕产妇抽血行变应原检测,确诊为变应性鼻炎的作为治疗组,给予鼻腔冲洗治疗,另将35名非孕产妇经同种检测手段确诊为变应性鼻炎的患者作为对照组,给予鼻腔冲洗联合鼻用激素治疗,观察各组治疗前、治疗3个月后鼻部症状视觉模拟量表(VAS)评分和鼻炎结膜炎生活质量(RQLQ)评分。结果两组患者治疗前VAS RQLQ评分比较差异无统计学意义(P>0.05),表明具有可比性。治疗3个月后两组患者VAS RQLQ评分均明显降低(P<0.05)。治疗3个月后VAS RQLQ评分减少差值比较,两组差异无统计学意义。结论鼻腔冲洗能改善变应性鼻炎孕产妇的鼻部症状,提高孕产妇AR的生活质量和孕期安全,为孕产妇AR患者提供了一种安全的治疗方法。

Objective To investigate the effect of nasal irrigation in the treatment of allergic rhinitis,and to explore the role ofnasal irrigation in the treatment of allergic rhinitis（AR）in pregnant women. Methods：will 35 cases of maternal blood,skin pricktest（SPT）diagnosed as allergic rhinitis as treatment group and intranasal irrigation treatment,another will be 35 non pregnant womenof the same detection diagnosis for allergic rhinitis patients as control group,intranasal use hormone therapy combined with nasal irri-gation,observation and treatment of the two groups before and after treatment,3 months nasal symptoms,visual analogue scale（VAS）and Rhinoconjunctivitis Quality of life（RQLQ）score. Results：there was no significant difference in RQLQ VAS scores be-tween the two groups before treatment（P〈0.05）,which showed that there was no significant difference between the groups. After 3months of treatment,the RQLQ VAS scores of the two groups were significantly lower（P〈0.05）. After 3 months treatment,the differ-ence of RQLQ VAS score was compared,and the difference between the two groups was not statistically significant. Conclusion：na-sal irrigation can improve maternal allergic rhinitis nasal symptoms,improve maternal ar life quality and pregnancy safe,provides asafe method of treatment for maternal ar patients.