摘要
目的:探讨用替普瑞酮治疗酒精相关性胃炎的临床效果。方法:对近年来我院收治的100例酒精相关性胃炎患者的临床资料进行回顾性研究。我们根据用药方案的不同将这100例患者分为硫糖铝组和替普瑞酮组,每组各有50例患者。我院为硫糖铝组患者使用硫糖铝片进行治疗,为替普瑞酮组患者使用替普瑞酮胶囊进行治疗。治疗结束后,比较两组患者治疗的效果及不良反应的发生率。结果:硫糖铝组患者治疗的总有效率为70%,替普瑞酮组患者治疗的总有效率为90.00%,替普瑞酮组患者治疗的总有效率明显高于硫糖铝组患者,二者相比差异具有显著性(P<0.05)。硫糖铝组患者不良反应的发生率为12%,替普瑞酮组患者不良反应的发生率为10.00%,二者相比无显著性差异(P>0.05)。结论:用替普瑞酮治疗酒精相关性胃炎的临床效果显著,且患者不良反应的发生率较低。此疗法值得在临床上推广应用。
Objective： To investigate the clinical effect teprenone in alcohol-related gastritis patients. Methods in our hospital in January 2012 - January 2015 were treated 100 cases of alcohol-related gastritis data analysis, patients were randomly divided into a control method in the control group and the observation group, the control group, sucralfate tablets treatment, observation teprenone treatment group were two groups were compared the efficacy and adverse drug reactions. Results observation group total effective rate was 90.00%, significantly higher （total effective rate 70.00%） （P 〈0.05）; observation group adverse drug reactions was 10.00%, compared to the control group and the difference was not significant （the occurrence of adverse drug reactions was 12.00%） （P〉 0.05）. Conclusion： The patients with alcohol-related gastritis teprenone ideal treatment can improve patients overall efficiency, lower incidence of adverse drug reactions, should be widely applied.
