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儿童急性淋巴细胞白血病的生物学特征 被引量:8

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摘要 儿童急性淋巴细胞白血病(acute lymphoblastic leukemia,ALL)占儿童急性白血病的75%~80%。根据淋巴细胞类型,ALL可分为急性B淋巴细胞白血病(BALL)和急性T细胞白血病(T-ALL),其中B-ALL占85%,T-ALL占15%。B-ALL的预后较T-ALL相对好。在目前规范、先进的治疗方案下,缓解率可达到90%以上,
作者 张晓晓 于洁
出处 《现代医药卫生》 2016年第9期1349-1352,共4页 Journal of Modern Medicine & Health
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  • 1Schultz KR, Carroll A, Heerema NA, et al. Long-term follow-up of ima- tinib in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia:Children's Oncology Group study AALL0031 [J]. Leukemia, 2014,28(7) : 1467-1471.
  • 2Mullighan CG, Goorha S, Radtke I, et al. Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia[J]. Nature, 2007,446 (7137) : 758-764.
  • 3O'Reilly J, Russell LJ, Cooney J, et al. Unravelling the prognostic effect of IKZF1 deletions and IGH@-CRLF2 in adult acute lymphoblastic leukae- mia [J]. Pathology ,2013,45 (6) :609-612.
  • 4Vitanza NA, Zaky W, Blum R, et al. Ikaros deletions in BCR-ABL-nega- tive childhood acute lymphoblastic leukemia are associated with a distinct gene expression signature but do not result in intrinsic chemoresistance[J]. Pediatr Blood Cancer,2014,61 (10) : 1779-1785.
  • 5Mullighan CG, Zhang J, Harvey RC, et al. JAK mutations in high-risk ehildhood acute lymphoblastic leukemia[J]. Proc Natl Acad Sci USA,2009, 106(23) :9414-9418.
  • 6Mullighan CG, Collins-Underwood JR, Phillips LA, et al. Rearrangementof CRLF2 in B-progenitor- and Down syndrome-associated acute lympho- blastic leukemia[J]. Nat Genet, 2009,41 ( 11 ) : 1243-1246.
  • 7Rand V, Parker H, Russell LJ, et al. Genomic characterization implicates lAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia[J]. Blood, 2011,117 (25) : 6848-6855.
  • 8Buitenkamp TD, Izraeli S, Zimmermann M, et al. Acute lymphoblastic leukemia in children with Down syndrome:a retrospective analysis from the Ponte di Legno study group[J]. Blood, 2014,123 ( 1 ) :70-77.
  • 9Hertzberg L, Vendramini E, Ganmore I, et al. Down syndrome acute lym- phoblastic leukemia,a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2:a report from the International BFM Study Group[J]. Blood, 2010,115 (5) : 1006-1017.
  • 10Jenkinson S, Koo K, Mansour MR, et al. Impact of NOTCH1/FBXW7 mu- tations on outcome in pediatric T-cell acute lymphoblastic leukemia pa- tients treated on the MRC UKALL 2003 trial[J]. Leukemia, 2013,27 (1) : 41-47.

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