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由CRISPR-Cas介导的细菌和古细菌的适应性免疫系统 被引量:1

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摘要 最新研究发现,微生物有一套以核酸为基础的适应性免疫系统,这改变了之前研究者认为的微生物免疫系统仅局限于固有免疫系统的认识。细菌与古细菌通过整合外源性核酸片段到宿主染色体成簇的规律间隔的短回文重复序列(Clustered regularly interspaced short palindromic repeat sequences,CRISPR)一端,从而获得对病毒及质粒的抗性。
出处 《中国免疫学杂志》 CAS CSCD 北大核心 2016年第4期605-608,共4页 Chinese Journal of Immunology
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