不同来源标本病原菌菌种的分布特点

Distribution of Pathogenic Bacteria Strains from Different Clinical Specimens

目的分析对比2011年-2013年不同来源标本的病原菌菌种分布特点,以期为感染的早期诊断和治疗提供临床参考。方法以2011年1月-2013年12月期间临床送检培养标本中分离的病原菌8083株为研究样本,统计不同感染部位的各病原菌菌种检出数和构成比。结果 2011年-2013年,各年度感染的主要病原菌种类及构成比相近。2011年从呼吸道标本分离的病原菌中检出数最多的菌种为念珠菌等酵母样真菌,占22.0%;2012年和2013年铜绿假单胞菌检出最多,分别占20.0%、22.1%。各年度从血样标本分离的病原菌中,构成比最大的菌种均为大肠埃希菌,分别占30.3%、25.9%、22.9%;各年度从尿样标本分离的病原菌中,构成比最大的菌种均为大肠埃希菌,分别占29.7%、33.4%、34.4%。结论医院内不同部位感染的主要病原菌种类及所占比例相对稳定,不同种类的标本之间病原菌分布有较大区别。

Objective To analyze the distribution of strains of pathogenic bacteria from different sources specimens, so as to provide clinical reference in early diagnosis, treatment for infection. Methods A total of 8083 strains of pathogenic bacteria were separated from clinical inspection training specimens from January 2011 to De- cember 2013, the species and constituent ratio of pathogenic bacteria strains from different infection positions was analyzed. Results The species and constituent ratio of pathogenic bacteria separated from clinical specimens were similar from 2011 to 2013. The strain of pathogenic bacteria separated from respiratory specimens was mainly candi- da and the other yeast fungal in 2011 （ accounted for 22.0% ） , P. aeruginosa in 2012 and 2013 （20.0% , 22.1% respectively）. The strain from the bloodstream specimens was mainly E. eoli in 2011,2012, and 2013, accounted for 30.3% , 25.9% ,and 30.3% respectively. E. eoli was mainly urinary tract infection pathogens too in 2011, 2012, and 2013, accounted for 29.7% , 33.4% , and 29.7% respectively. Conclusion The species and constituent ratio of pathogenic bacteria separated in hospital is relatively stable, the distribution of pathogenic bacteria has great difference between different kinds of clinical specimens.