腧穴热敏化悬灸治疗腹泻型肠易激综合征临床研究

Clinical Study of Acupoint Heat-sensitive Suspended Moxibustion Therapy for Treatment of Diarrhea-predominant Irritable Bowel Syndrome

【目的】比较腧穴热敏化悬灸与口服西药治疗腹泻型肠易激综合征(IBS-D)的临床疗效差异。【方法】采用随机数字表法将80例符合纳入标准的IBS-D患者随机分为治疗组和对照组各40例,治疗组采用腧穴热敏化悬灸治疗,对照组采用口服马来酸曲美布汀胶囊治疗,2组治疗时间均为4周,观察并记录治疗前后IBS-D主要症状体征(腹痛、腹胀、排便次数、稀烂便)积分变化,评价2组临床疗效及安全性。【结果】(1)治疗4周后,2组患者的各项主要临床症状评分及总积分均较治疗前显著改善(P<0.01),且治疗组在改善患者的各项主要临床症状评分及总积分方面均优于对照组(P<0.05或P<0.01)。(2)在疗效方面,治疗组的总有效率为85.0%,优于对照组的67.5%,差异有统计学意义(P<0.05)。(3)在安全性方面,2组在治疗后均未出现任何不良反应。【结论】腧穴热敏化悬灸疗法治疗IBS-D临床疗效显著,安全性良好。

Objective To compare the clinical efficacy of acupoint heat-sensitive suspended moxibustion therapy and oral administration of western medicine in treating diarrhea-predominant irritable bowel syndrome（IBS-D）.Methods Random number tables were used for the randomization of 80 patients which met the inclusion criteria.The patients were randomly divided into treatment group and control group, 40 cases in each group. The treatment group was treated by acupoint heat-sensitive suspended moxibustion therapy,while the control group was treated with oral use of trimebutine maleate capsules. The treatment for the two groups covered 4 weeks.Before and after treatment, we investigated the scores of main symptoms and signs of IBS-D to evaluate the clinical efficacy and safety of both groups. Results（1）After treatment for 4 weeks,the scores of main symptoms and signs as well as their overall scores in the two groups were improved（P〈0.01 compared w ith those before treatment）,and the effect of treatment group was superior to that of the control group（P〈0.05 or P〈0.01）.（2）The total effective rate of the treatment group was 85.0%,and that of the control group was 67.5%,the difference being statistically significant（P〈0.05）.（3） Both groups showed no adverse reaction. Conclusion Acupoint heat-sensitive suspended moxibustion therapy is effective and safe for the treatment of IBS-D.