摘要
目的了解高邮市2009-2014年狂犬病暴露者接种狂犬疫苗的效果。方法 11 951例暴露者全程接种狂犬病疫苗10-15d后,以酶联免疫吸附试验（ELISA）测定血清狂犬病抗体。结果 11 951份血清标本,阳性11 587份,总阳性率96.95%。其中男性阳性率96.31%;女性阳性率97.62%;男女之间差异有统计学意义（χ^2=16.91,P〈0.05）。各年龄组之间阳性率差异有统计学意义（χ^2=227.43,P〈0.05）。结论全程接种狂犬病疫苗后,96.95%以上的患者抗狂犬病毒抗体水平合格,还有3.05%的患者抗体水平低于保护阈值,需进一步加强接种,才能保证免疫效果。
Objective This paper investigates vaccinated rabies vaccine effect among the patients exposed to rabies in Gaoyou city from 2009-2014. Methods 11 951 cases after exposure to the entire rabies vaccination 10-15 d are determined for serum antibody against rabies virus by enzyme linked immunosorbent assay（ ELISA） method. Results Among the 11 951 serum samples,the positive cases are 11 587,with a rate of 96. 95%. The positive rate of male is 96. 31%; female positive rate is 97. 62%. The difference between the male and the female is statistically significant（ chi square = 16. 91,P〈0. 05）. Difference of positive rate between each age group has statistics significance（ χ~2= 227. 43,P〈0. 05）. Conclusion After the vaccination of rabies vaccine,more than 96. 95% patients are with the anti rabies virus antibody of qualified level. 3. 05% patients are with antibody levels below the threshold of protection,and need to be strengthened by further inoculation,in order to ensure the immune effect.
出处
《口岸卫生控制》
2016年第2期58-59,共2页
Port Health Control
关键词
狂犬病
狂犬疫苗
抗体检测
Rabies
rabies vaccine
antibody determination
