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绿色荧光裸小鼠睾丸组织学观察及精子质量检查 被引量:2

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摘要 目的探讨绿色荧光裸小鼠繁殖率低下的原因。方法对绿色荧光裸小鼠的睾丸及附睾进行组织病理学及精子质量检查。比较雄性绿色荧光裸小鼠与BALB/c裸小鼠的睾丸、附睾脏器系数和精子浓度、精子活力、活率及精子畸形率;观察睾丸及附睾组织病理学变化。结果雄性绿色荧光裸小鼠及BALB/c裸小鼠的睾丸、附睾脏器系数、精子浓度及组织结构并无显著差异(P〉0.05);但精子活力(直线运动和原地转动及静止不动)的构成比、活精子率及畸形率间均具有显著差异(P〈0.05)。结论雄性绿色荧光裸小鼠精子质量(活力、活率及畸形率等方面)略为低下可能是影响绿色荧光裸小鼠繁殖性能的原因之一。
出处 《实验动物与比较医学》 CAS 2016年第2期126-128,共3页 Laboratory Animal and Comparative Medicine
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