ICU呼吸机相关性肺炎危险因素与预防策略分析

Risk Factors and Prevention Strategy of Ventilator Associated Pneumonia in ICU

目的:探讨ICU呼吸机相关性肺炎(VAP)的危险因素及其预防策略。方法:选取2012年5月-2015年5月本院收治的ICU呼吸机治疗患者420例作为研究对象,根据有无VAP分为VAP组200例与非VAP组220例,比较两组一般情况,总结VAP危险因素,并制定合理的预防策略。结果:两组在血白蛋白、机械通气时间、抗生素联用种类、再次插管率、神志昏迷率、病死率及APACHEⅡ评分上比较差异均有统计学意义(P<0.05)。结论:多次插管、机械通气时间、神志昏迷及APACHEⅡ评分≥15分属于ICU呼吸机相关性肺炎危险因素,临床需加强重视。

Objective：To explore the risk factors and prevention strategies of ICU ventilator associated pneumonia（VAP）.Method：From May 2012 to May 2015,420 patients with ventilator therapy in our hospital ICU were selected as the research objects,they were divided into the VAP group of 200 cases and the non VAP group of 220 cases according to whether had or not had VAP.The general situation of the two groups were compared,the risk factors of VAP were summarized and the reasonable prevention strategy were established.Result：There were statistically significant in serum albumin,duration of mechanical ventilation,antibiotics combined with species,reintubation rate,delirious rate,mortality rate and APACHE II score（P〈0.05）.Conclusion：Multiple intubation,mechanical ventilation time,delirious and APACHE II score greater than or equal to 15 points belongs are risk factors of ICU ventilator associated pneumonia,which need to strengthen clinical attention.