摘要
目的:观察盐酸甲哌卡因在儿童乳牙拔除中的麻醉效果。方法:将451例临床诊断为乳牙滞留,需要拔除乳牙的患儿随机分为试验组226例和对照组225例,试验组和对照组分别采用盐酸甲哌卡因和2%盐酸利多卡因局部浸润麻醉,对两组患儿分别在注射后2 min、5 min和10 min时用探针在牙周进行疼痛测试的反应、麻醉注射过程中的疼痛评分以及拔牙过程中麻醉效果进行评价。结果:盐酸甲哌卡因与利多卡因相比,麻醉起效时间短,麻醉注射过程中疼痛轻,差异有统计学意义(P<0.05)。盐酸甲哌卡因麻醉总有效率为96.90%,高于利多卡因麻醉总有效率(87.55%),差异有统计学意义(P<0.05)。结论:盐酸甲哌卡因应用于儿童乳牙拔除中的局部浸润麻醉,起效时间快、注射过程中疼痛小,麻醉效果较好,值得临床推广。
Objective: To investigate the anesthesia effects of mepivacaine hydrochloride on children's deciduous teeth extraction.Methods: A total of 451 children were diagnosed as retainted deciduous teeth,and randomly divided into experimental group( n = 226)and control group( n = 225). In the experimental group,children were injected with mepivacaine hydrochloride,and in the control group children were injected with lidocaine. After injected 2 min,5 min and 10 min,children were taken in pain tests,the pain degree during the injection and the anesthesia effects during extraction were recorded. Results: The onset time of anesthesia was shorter in experimental group than control group( P0.05). The pain of injection was mild in experimental group than control group( P 0.05). The effective rate was 96.90% in experimental group and 87.55% in control group,there was statistically difference between two groups( P 0.05).Conclusion: Mepivacaine hydrochloride can shorten the onset time of anesthesia,reduce the pain of injection. The anesthesia effects of mepivacaine hydrochloride on children's deciduous teeth extraction are good.
出处
《儿科药学杂志》
CAS
2016年第5期22-24,共3页
Journal of Pediatric Pharmacy
关键词
盐酸甲哌卡因
利多卡因
乳牙拔除
局部浸润麻醉
mepivacaine hydrochloride
lidocaine
deciduous teeth extraction
local infiltration anesthesia