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儿童失神癫痫研究进展 被引量：2

Progress of Absence Epilepsy in Children
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摘要 儿童失神癫痫（Children absence epilepsy,CAE）是一种全身特发性癫痫,以频繁典型失神发作、双侧对称同步3 Hz节律性棘慢波放电为特征。在儿童中,其患病率为0.4/1 000~0.7/1 000[1],约占儿童癫痫的5%~15%;发病率为5.8/100 000~7.1/100 000[2],女孩发病率比男孩发病率高;起病通常在4~10岁之间,以5~7岁为发病高峰年龄^（[3]）。
作者 黄中燕 黄志
机构地区 重庆医科大学附属儿童医院
出处 《儿科药学杂志》 CAS 2016年第5期54-57,共4页 Journal of Pediatric Pharmacy
关键词 儿童失神癫痫 典型失神发作 棘慢波放电 EPILEPSY 高峰年龄 乙琥胺 棘波 肌阵挛发作 丙戊酸 棘慢复合波
分类号 R742.1 [医药卫生—神经病学与精神病学]
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参考文献33

  • 1JALLON P, LATOUR P. Epidemiology of idiopathic generalized epilepsies [ J ]. Epilepsia, 2005, 46 ( Suppl 9) : 10-14.
  • 2OLSSON I. Epidemiology of absence epilepsy. I. Concept and incidence [J]. Acta Paediatr Scand, 1988, 77(6): 860-866.
  • 3PANAYIOTOPOULOS C P. Idiopathic generalized epilepsies. In: PANAYIOTOPOULOS C P, ed. The Epilepsies : Seizures, Syndromes and Management [M]. Oxford, UK : Bladon Medical Publishing, 2005.
  • 4VRIELYNCK P. Current and emerging treatments for absence seizures in young patients [ J]. Neuropsychiatr Dis Treat, 2013, 9 : 963-975.
  • 5ALBINI M, MORANO A, FANELLA L, et al . Effectiveness of rufinamide in the treatment of idiopathic generalized epilepsy with atypical evolution : case report and review of the literature [ J ]. Clin EEG Neurosci, 2014, 23. pii: 1550059414559940.
  • 6PANAYIOTOPOULOS C P. Childhood absence epilepsy [ EP/ OL]. www. epilepsy, org/etf/childhood_absencehtml. 2000.
  • 7马秀伟,张月华,杨志仙,刘晓燕,孙慧慧,姜玉武,秦炯,吴希如.儿童失神癫的临床和视频脑电图特点与诊断标准探讨[J].实用儿科临床杂志,2009,24(7):529-532. 被引量：8
  • 8HIRSCH E, PANAYIOTOPOULOS C P. Childhood absence epilepsy and related syndromes. In: ROGER J, BUREAU M, DRAVET C, et al. Epileptic Syndromes in Infancy, Childhood and Adolescence [ M ]. 4th ed. Montrouge, France: John Libbey Eurotext Ltd, 2005.
  • 9BLUMENFELD H. CeUular and network mechanisms of spike- wave seizures [J]. Epilepsia, 2005, 46(Suppl 9): 21-33.
  • 10GAMBARDELLA A, LABATE A. The role of calcium channel mutations in human epilepsy [J]. Prog Brain Res, 2014, 213: 87 -96.

二级参考文献39

  • 1Engel J. A proposed diagnostic scheme for people with epileptic seizures and with epilepsy : Report of the ILAE task force on classification and terminology [ J ]. Epilepsia,2001,42 ( 6 ) :796 - 803.
  • 2Panayiotopoulos CP. Syndromes of idiopathic generalized epilepsies not recognized by the International League Against Epilepsy [ J ]. Epilepsia, 2005,46(9) : 57 -66.
  • 3Commission on Classification and terminology of the International League Against Epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes [ J ]. Epilepsia, 1989,30 ( 4 ) : 389 - 399.
  • 4Panayiotopoulos CP. Idiopathic generalized epilepsies [ M ]//Panayiotopoulos CP. The epilepsyies: Seizures, syndromes and management. Oxford: Bladon Medical Publishing,2005:296 -303.
  • 5Valentin A, Hindoeha N, Osei - Lab A, et al. Idiopathic generalizedepilepy with absences : Syndrome classification [ J ]. Epilepsia, 2007,48 (11) : 2187 -2190.
  • 6Shahar E, Genizi J, Nero Y, et al. Typical absence epilepsy presenting prior to age of 3 years : An uncommon form of idiopathic generalized epilepsy [J]. Eur J Paediatr Neurol,2007,11 (6) :346 -352.
  • 7Fernandez - Torre JL, Herranz JL, Martinez - Martinez M, et al. Early - onset absence epilepsy:Clinical and electroencephalographic features in three children[J]. Brain Dev,2006,28(5) : 311 -314.
  • 8Callenbach PM, Bouma PA, Geerts AT, et al. Long- term outcome of childhood absence epilepsy:Dutch study of epilepsy in childhood [ J]. Epilesy Res ,2009,83 ( 2 - 3 ) :249 - 256.
  • 9Sadleir LG, Farrell K, Smith S, et al. Electroclinical features of absence seizures in childhood absence epilepsy [ J ]. Neurology, 2006,67 ( 3 ) : 413 -418.
  • 10Grosso S, Galimberti D, Vezzosi P, et al. Childhood absence epilepsy: Evolution and prognostic factors [ J ]. Epilepsia,2005,46 ( 11 ) : 1796 - 1801.

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儿科药学杂志
2016年 第5期

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