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左卡尼汀对慢性肾衰竭非透析患者蛋白质能量消耗的影响 被引量:13

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摘要 研究发现在慢性肾衰竭患者中普遍存在蛋白质能量消耗,严重影响患者的生活质量与预后,积极防治蛋白质能量消耗有助于延缓慢性肾衰竭的进展^([1^3])。近年来研究提示,左卡尼汀,即左旋肉毒碱,是长链脂肪酸从胞质转运人线粒体内膜进行氧化所必需的一种物质,可促进ATP产生而提供能量,同时也有促进蛋白降解、抗氧化、保护细胞膜等作用,与代谢疾病、心血管疾病、神经系统疾病、肝脏疾病及肾脏疾病有关^([4,5])。
作者 刘新荪
出处 《中国中西医结合肾病杂志》 2016年第4期340-341,共2页 Chinese Journal of Integrated Traditional and Western Nephrology
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参考文献7

  • 1Kovesdy CP, Kopple JD, Kalantar - Zadeh K. Management of pro- tein - energy wasting in non - dialysis - dependent chronic kid- ney disease:reconciling low protein intake with nutritional thera- py. Am J Clin Nutr,2013,97(6) :1163 -1177.
  • 2Carrero JJ, Stenvinkel P, Cuppari L, et al. Etiology of the protein-energy wasting syndrome in chronic kidney disease:a consen- sus statement from the International Society of Renal Nutrition and Metabolism (ISRNM). J Ren Nutr,2013,23(2) :77 -90.
  • 3Jadeja YP, Kher V. Protein energy wasting in chronic kidney dis- ease : An update with focus on nutritional interventions to improve outcomes. Indian J Endocrinol Metab,2012,16 (2) : 246 - 251.
  • 4Kepka A, Chojnowska S, Snitko R, et al. Renal carnitine excretion following abstinence after chronic drinking. Adv Med Sci,2015, 61(1) :160 - 163.
  • 5Guarnieri G. Carnitine in maintenance hemodialysis patients. J Ren Nutr ,2015,25 ( 2 ) : 169 - 175.
  • 6Fouque D, Kalantar - Zadeh K, Kopple J, et al. A proposed no- menclature and diagnostic criteria for protein - energy wasting in acute and chronic kidney disease. Kidney Int,2008,73 (4) :391 - 398.
  • 7乔艳红,刘虹.左卡尼汀与慢性肾衰竭[J].长治医学院学报,2008,22(2):151-153. 被引量:13

二级参考文献11

  • 1Borum PR,Plasma carnitine compartment and red blood cell curnitine compartment of healthy adults[J]. Am J Clin Nutr, 1987,46:437-441.
  • 2Goa KL, Brogckn RN. L - carnitine: a preliminary review of its pharmaco kinetics and its therapeutic use in lischaemic cardiac disease and primary and secondary carnitine deficiencies in relationship to its role in fatty acid metabolism. Drugs, 1987,34:21-24.
  • 3Arduine A,Holme S,Sweeney JD,et al. Addition of L- carnitine to additire solutiorr - suspended red cell stored at 40 c reduces in vitro hemolysis and improves in vivoviability [ J ]. Transfusion, 1997,37: 166-174.
  • 4Donatelli,M,Terrizzi C,Zumro G,Russo V,Bucdo M,Scarpinaro A, Effects o L - earnitine on chronic anemia and adenosine triphosphate concentration in hemodialyzed patients. Curv Ther Res, 1987,41 : 620-624.
  • 5Agroyannis B,Parakeropoulos A,Fourtounas C, et al .Effect of L - carnitine on the calcium contant of erythrocytes of uremic patients on hemodialysis. Dial Transplant 2002,31 : 106-128.
  • 6Kletzmayr J,Mayer G,legenstein E,et al. Ancmia and carmitine supplementation in hemodialyzed patients [ J ]. Kidney Int, 1999, 55 (69):93-106.
  • 7Mastsumura M,Hatakeyama S,Kon:J, et al .Correlation between serum carnitine levels and erythrocyte osmotic fragility in hemodialysis patients [J]. Nephron, 1996,72: 574-578.
  • 8Labonia WD. L- canitine effects on anemia in hemodialy patients treated with eryshropoietin [ J ]. Am J Kidncy Dis, 1995,26 (5) : 757-764.
  • 9Romagnoli GF,Naso A,Carraro G,Lidcstri V: Beneficial effects of L- carnitine in dialysis patients with impaired left, ventricalar function: An observational study: Curr Med Res Opin, 2002,18: 172-175.
  • 10Sloan RS, Kastan B, Rice SI, et al. Quality of llfe dunry and between hemodlalysis treatments: role of L - eamitine supple mentaltion [J].Am J Kidney Dis, 1998,32:265-278.

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