闭式胸膜活检在胸腔积液病因诊断中的应用

Clinical Value of Closed Pleural Biopsy in the Etiological Diagnosis of Pleural Effusion

目的:探讨闭式胸膜活检在胸腔积液病因诊断中的临床应用价值。方法:以50例病因未明胸腔积液患者为研究对象,均先后行常规、生化及细胞学检查及闭式胸膜活检。观察分析闭式胸膜活检取材成功率、诊断阳性率及并发症发生情况。结果:1闭式胸膜活检首次取材成功率为92.6%;2常规、生化检验胸腔积液病因检出率为46.0%,明显低于同闭式胸膜活检胸腔积液病因检出率68.0%,对比差异具有统计学意义(P<0.05);3两者并发症比较,并无显著差异(P>0.05)。结论:闭式胸膜活检应用于胸腔积液病因诊断临床,具有操作简便易行、安全度高、创伤小等优势,且阳性诊断率高。

Objective To investigate the clinical value of closed pleural biopsy in the diagnosis of pleural effusion. Methods 50 cases of unknown etiology patients with pleural effusion as the research object,first underwent routine,biochemical and cytological examination and closed pleural biopsy. Observed and analyzed the success rate,positive rate and complication of closed pleural biopsy. Results ①The successful rate of closed pleural biopsy was 92. 6%; ②Normal,biochemical tests pleural effusion etiology detection rate was 46. 0%,significantly lower than with enclosed pleural biopsy,pleural effusion etiology detection rate 68. 0% contrast differences statistically significant（ P〈0. 05）; ③ both complications,and no significant difference（ P〉0. 05）. Conclusion Closed pleural biopsy in the diagnosis of pleural effusion etiology clinical,has the advantages of easy operation,high safety,small trauma,and the positive rate of diagnosis,with the promotion of significance.