药物疗法与器械疗法治疗门脉高压致食管静脉曲张破裂出血患者的疗效比较

Effect of Drug Therapy and Instrument Therapy on Bleeding of Esophageal Varices in patients with Portal Hypert-ension

目的:比较药物疗法与器械疗法在治疗门脉高压致食管静脉曲张破裂出血的临床应用效果。方法:选取100例于门脉高压致食管静脉曲张破裂出血患者作为研究对象,将其随机分为对照组和观察组两组,每组50例。其中,对照组行药物疗法治疗;观察组行器械疗法治疗。治疗后,比较两组的临床疗效、不良反应发生率以及复发率。结果:观察组临床疗效总有效率明显高于对照组,而其不良反应发生率与复发率明显低于对照组,差异均具有统计学意义(P<0.05)。结论:与药物疗法相比,器械疗法治疗门脉高压致食管静脉曲张破裂出血的临床疗效更好,安全性更高,值得临床推广应用。

Objective To compare the clinical effect of drug therapy and device therapy in the treatment of esophageal varices bleeding caused by portal hypertension. Methods 100 cases of esophageal varices bleeding patients with portal hypertension were selected as the subjects of this study,they were randomly divided into two groups,control group and observation group,50 cases in each group. Among them,the control group were given drug therapy,the observation group were treated with instrument therapy. After treatment,the clinical efficacy,incidence of adverse reactions and recurrence rate of the two groups were compared. Results The total effective rate of the observation group was significantly higher than that of the control group,and the incidence of adverse reactions and recurrence rate was significantly lower than the control group,the difference was statistically significant（ P〈0. 05）. Conclusion Compared with drug therapy,the treatment of portal hypertension patients with esophageal varices bleeding clinical curative effect is better,the safety is higher,it is worthy of clinical application.