试论小剂量胺碘酮联合酒石酸美托洛尔对老年心律失常患者的治疗效果

The Effect of Low Dose Amiodarone Combined With Metoprolol Tartrate in the Treatment of Elderly Patients With Arrhythmia

目的分析探讨小剂量的胺碘酮联合酒石酸美托洛尔（倍他乐克）对老年心律失常患者进行治疗的临床疗效。方法选取2014年9月~2015年9月120例老年心律失常患者,随机均分为对照组（n=60）和观察组（n=60）。对照组采取单纯倍他乐克治疗,观察组采取小剂量的胺碘酮联合倍他乐克治疗。观察两组患者治疗结果。结果治疗后,观察组患者有效率达93.3%,高于对照组70.0%,两组数据比较,差异具有统计学意义（χ2=10.909 1,P=0.001 0）。对照组患者心率恢复至正常水平的时间晚于观察组患者（χ2=8.704 7,P=0.000 0）。观察组患者发生不良反应的患者例数低于对照组患者例数（χ2=11.582 0,P=0.000 7）。结论采用小剂量胺碘酮结合倍他乐克治疗老年心律失常患者,能有效改善患者不良症状。

Objective To analyze the effect of low dose amiodarone combined with metoprolol tartrate in the treatment of elderly patients with arrhythmia. Methods 120 cases of elderly patients with arrhythmia from September 2014 and September 2014 in our hospital were randomly divided into the control group（n = 60）and the observation group（n = 60）. The control group were treated with pure tartaric acid metoprolol（betaloc）treatment,the observation group were treated with small doses of amiodarone combined with betaloc treatment. Observed the effect of two groups of patients. Results After treatment,the total effective rateof the observation group was（93.3 %）,obviously higher than that of control group（70.0%）,the difference was statistically significant（χ2=10.909 1,P=0.001 0）. The control group patients with heart rate back to normal time was later than the observation group（χ2=8.704 7,P=0.000 0）. The observation group of patients with adverse reactions was significantly lower than the control group（χ2=11.582 0,P=0.000 7）. Conclusion Low dose amiodarone combined with metoprolol tartrate in the treatment of elderly patients with arrhythmia can effectively improve patients＇ adverse symptoms.