不同剂量孕激素治疗无排卵型月经失调对比分析

Comparative Analysis of Different Doses of Progesterone for Menstrual Disorder of Anovulatory Group

目的分析不同剂量孕激素在治疗无排卵型月经失调中的疗效。方法选取2014年8月~2015年2月我院收治符合无排卵型月经失调诊断标准的患者80例,将所有患者随机分为A、B、C、D 4组,给予A组100 mg、B组200 mg、C组300 mg、D组400 mg口服黄体酮治疗,分析比较4组治疗效果。结果对4组治疗疗效对比中,4组治疗疗效差异无统计学意义（P〉0.05）;在不良反应对比中,A组不良反应低于其他3组,差异具有统计学意义（P〈0.05）;经过治疗后,4组患者出血量均得到有效的控制,组间差异无统计学意义（P〉0.05）。结论不同剂量的孕激素在治疗无排卵型月经失调中均取得良好的治疗效果,考虑药物使用剂量安全性应给予患者最低剂量的孕激素,以达到安全、高效的临床效果。

Objective To analyze the treatment effect of menstrual disorder treated by different dose of progestational hormone. Methods To selected 80 cases of patients conformed to the standard of menstrual disorder at our hospital from August 2014 to February 2015,to randomly divided into the group A, B,C and D that 4 groups. The group A was given 100 mg, group B was 200 mg,the group C was 300 mg and the group D was 400 mg of the progesterone. To analyzebthe treatment effect. Results To compared the treatment effect,there was no statistical significance（P〈0.05）. To compared the adverse reactions,the group A was lower than the other three groups,there was statistical significance（P〈0.05）. After treatment,the amount of bleeding was controlled of them,there was no statistical significance（P〈0.05）. Conclusion That all has the favourable treatment effect of the different dose of progesterone for the menstrual disorder of anovulatory group,there should to given the lowest dose level of progestational hormone that considered the safety of using dose,so that to reach the clinic effect of safety and efficient.