免疫细胞在女性生殖器官中的分布及意义

Distribution And Significance of Immunocytes in the Female Cenital Organs

在女性生殖器官中，Ｔ淋巴细胞分布在子宫、卵巢、输卵管、宫颈、阴道及外阴组织中。在子宫内膜及卵巢卵泡液中，其变化与局部免疫机制有关。子宫内膜中还有颗粒淋巴细胞和抑制细胞分布，二者在妊娠蜕膜内明显增加，推测与早孕及妊娠成功有关。巨噬细胞在上述生殖器官中也有分布，其数量及分布受性激素调节。郎格罕细胞主要分布于宫颈、阴道及外阴的复层扁平上皮，其作用是作为Ｔ淋巴细胞的抗原提呈细胞。胎儿能够在母体存活，可能与子宫内膜Ｔ_４／Ｔ_８比值，颗粒淋巴细胞和抑制细胞的分布有关，其机制有待进一步研究。

T-lymphocytes are distributed in the uterus, ovary, oviduct, cervicalis, colpo and vulva tissues of the female organs. Their changes in the uterine mucosa and ovarian filliculater fluid are related to the local immunity mechanism. Also distributed in the uterine mucosa are some granular lymphocytes and suppressor cells, both of which increase dramatically in gestation decidua, supposedly related to the success of pregnancy. The distribution of macrophage can also be found in the genital organs, but its number and distribution are adjusted by sexhormone. Langerhans cells are mainly distributed in the stratified squamous epithelium of cervicalis, colpo and vulua. The rcason why the foetus can survive in the mother’ s body may be related to the T4/T8 ratio of endometrium, and the distribution of granular lymphocytes and suppressor cells. And its mechanism remains to be researched further.