摘要
给小鼠脑室注射三氯化铝造成鼠脑急性铝中毒后，用被动回避性条件反应试验的跳台法及避暗法进行观察，发现在注射一周后小鼠出现了明显的记忆障碍。如在注射后第５天起每天口服尼莫地平，则能明显对抗三氯化铝引起的记忆障碍。另外，尼莫地平对东莨菪碱所致的学习记忆障碍亦有明显改善作用。
After the injection of ALCL3, to induce actual aluminum brain intoxication through intraventricular route for a week. the mice produced significant amnesia. But the mice which were administered nimodipine everyday since the 5th day of ALCL3 injection could counter the amnesia induced by ALCL3. In addition, nimodipine can also improve amnesia induced by scopolamine.
