摘要
对３１例ＳＬＥ患者Ｔ细胞亚群及血清ＳＩＬ－２Ｒ进行检测。结果显示：ＳＬＥ患者ＣＤ＋３、ＣＤ＋４以及ＣＤ＋４／ＣＤ＋８明显低于正常人（Ｐ＜００５），但与疾病的活动性无关。ＣＤ＋８无明显改变；ＳＩＬ－２Ｒ水平明显升高（Ｐ＜００５），且活动期ＳＩＬ－２Ｒ高于非活动期。提示ＳＬＥ患者细胞免疫功能紊乱，且非活动期患者免疫调节功能还未完全恢复，导致反复发作。检测ＳｌＬ－２Ｒ可作为判断疾病活动性的一个指标，亦可反映Ｔ淋巴细胞激活程度。
-cell group and SIL-2R in 31 SLE patients were tested.The results revealed that CD+3,CD+4 and CD+4/CD+8 of the patients were much lower than that of normal people (P<0.05),which was not related to the activity. SIL-2R in the active period is higher than that in the unactive period (P<0.05),but the change of CD+8 seems not obvious.It is suggested that the disorder of the cell immunity exists in SLE patients.The immuno-regulation in the unactive period does not recover completely and this gives rise to a repeated relapse. The detection of SIL-2R may be regarded as an index for determining the activity of the disease or reflexing the activity of T-cells.
