摘要
目的：通过复习文献，对获得性纯红细胞再生障碍性贫血（获得性ＰＲＣＡ）的临床特征，病因，发病机理及治疗现状进行探讨。方法：对手工检索的获得性ＰＲＣＡ的有关文献进行统计分析。结果：获得性ＰＲＣＡ病因与生物、化学因素及多种疾病有相关性，部分病因不明；治疗主要以糖皮质激素、细胞毒性药物、环孢毒素Ａ，及胸腺切除术联合治疗等。结论：获得性ＰＲＣＡ发病与多种因素有关，目前无满意的治疗方案，有必要进行更深入的研究。
Objective: To investigate the clinical features, etiology, pathogenesis and treatment of acquired Pure Red Cell Aplasia (PRCA) by review of the literature. Method: A statistic analysis of the articles reviewed was made. Result: There is a close relationship between the etiology of acquired PRCA and biological, chemical factors and other diseases. The treatment includes use of drugs as glucocorticoid, cytotoxics, cyclosporine A, and a combination with thymectomy. Conclusion: The incidence of acquired PRCA is related to various factors. Further study should be carried out before a satisfactory treatment can be found.
