早产儿不同类型脑损伤MRI演变规律评价中磁共振成像的应用及其意义

Application and significance of magnetic resonance imaging in different types brain injury preterm children by MRI evolution

目的:探讨不同类型早产儿脑损伤MRI演变规律评价中磁共振成像的临床价值。方法:对498例早产儿行常规MRI和DWI检查,确诊早产儿脑损伤302例,分析不同类型早产儿脑损伤MRI演变规律。结果:498例早产儿中经MRI和DWI诊断确诊为早产儿脑损伤302例,多表现为呼吸暂停、抽搐、反应抑制以及原始反射异常等,轻度患儿呼吸暂停和抽搐发生率均显著低于其他两组(P<0.05),脑损伤可出现在早期和中晚期早产儿中,I^III处损伤多是点状分布和线状分布,IV处呈现弥散性分布,损伤1周内,DWI高信号,1~3周复查病灶消失或者信号稍高、正常。结论:MRI能够动态监测各类型脑损伤,能够比较客观判断早产儿脑损伤预后。

Objective：To analyze and discuss the application and significance of Magnetic resonance imaging in different types brain injury preterm children by MRI evolution,and to provide reference for clinical diagnosis.Methods：498cases of premature children were retrospective analysised,patients were conventionaled MRI and DWI,302 cases of brain injury in premature children were diagnosed.Made of different types of brain MRI in preterm children evolution of damage was analyzed.Results：The clinical data of 498 cases of premature children were sorted by MRI and DWI diagnosis,302 cases diagnosed as brain damage in premature children.Brain injury in preterm children symptoms were apnea,withdrawn,response inhibition and primitive reflexes abnormalities,children with mild apnea and convulsions were significantly lower than the other two groups（P〈0.05）,brain damage may be in the early and middle in late preterm children,I^III injuries were mostly punctate distribution and linear distribution,IV diffuse distribution at the presentation.1week injury,DWI was high signal,1to 3weeks after the lesions disappear or signal slightly,normal.Conclusion：MRI able to objectively determine the prognosis of preterm children brain damage to the patient for early rehabilitation of important value.